Best local AI models for NVIDIA Quadro K4100M
4 GB GDDR5. At a 4k context, 81 of the 233 models in our catalog with verified parameter counts fit fully, up to Lumina-Next / Lumina-Image 2.0 at 5B parameters.
Check your own machine against every model →The largest models that fit fully
The 30 largest of the 81 models that fit; every smaller model in the catalog fits too. Best quant means the highest quality compression whose weights and 4k context both sit inside the memory.
| Model | Parameters | Best quant that fits | Memory used at 4k |
|---|---|---|---|
| Lumina-Next / Lumina-Image 2.0 | 5B | Q4_K_M | 3.7 GB |
| CogVideoX 2B / 5B | 5B | Q4_K_M | 3.7 GB |
| DeepSeek-VL2 | 4.5B | Q5_K_M | 3.8 GB |
| DeepFloyd IF | 4.3B | Q5_K_M | 3.7 GB |
| Phi-3.5-vision | 4.2B | Q5_K_M | 3.6 GB |
| Qwen3 4B | 4B | Q6_K | 3.9 GB |
| Gemma 3 4B | 4B | Q6_K | 3.9 GB |
| Gemma 4 E4B | 4B | Q6_K | 3.9 GB |
| MiniCPM 3 4B | 4B | Q6_K | 3.9 GB |
| Danube 3 4B | 4B | Q6_K | 3.9 GB |
| Fish Speech 1.5 / OpenAudio S1 | 4B | Q6_K | 3.9 GB |
| Phi-4-mini-instruct | 3.8B | Q6_K | 3.7 GB |
| Phi-3.5 Mini | 3.8B | Q6_K | 3.7 GB |
| OmniGen / OmniGen2 | 3.8B | Q6_K | 3.7 GB |
| SD Cascade (Würstchen v3) | 3.6B | Q6_K | 3.5 GB |
| SDXL Turbo | 3.5B | Q6_K | 3.4 GB |
| SDXL Lightning | 3.5B | Q6_K | 3.4 GB |
| ACE-Step | 3.5B | Q6_K | 3.4 GB |
| MusicGen small/medium/large | 3.3B | Q6_K | 3.2 GB |
| SmolLM3 3B | 3B | Q8_0 | 3.8 GB |
| Replit Code v1.5 3B | 3B | Q8_0 | 3.8 GB |
| Kandinsky 3.1 | 3B | Q8_0 | 3.8 GB |
| Voxtral Mini / Small | 3B | Q8_0 | 3.8 GB |
| Orpheus TTS | 3B | Q8_0 | 3.8 GB |
| Higgs Audio v2 | 3B | Q8_0 | 3.8 GB |
| Allegro | 2.8B | Q8_0 | 3.6 GB |
| Open-Sora Plan | 2.7B | Q8_0 | 3.4 GB |
| LFM2 1.2B / 2.6B | 2.6B | Q8_0 | 3.3 GB |
| Playground v2.5 | 2.6B | Q8_0 | 3.3 GB |
| Stable Diffusion 3.5 Medium | 2.5B | Q8_0 | 3.2 GB |
Close, but only with CPU offload
These need more than the card holds at their smallest practical quant, so part of the model runs from system memory (figures assume 32 GB of it). They work, several times slower.
| Model | Parameters | Memory at FP8 / optimized | System RAM at 4k |
|---|---|---|---|
| Stable Diffusion XL | 3.417B | 4.1 GB needed | 6.1 GB |
| Phi-3 Mini | 3.8B | 4.4 GB needed | 6.4 GB |
| Phi-4-multimodal | 5.6B | 4.1 GB needed | 6.1 GB |
| Magicoder-S-DS 6.7B | 6.7B | 4.9 GB needed | 6.9 GB |
| Mistral 7B | 7B | 5.7 GB needed | 7.7 GB |
| Qwen2.5 0.5B / 1.5B / 3B / 7B | 7B | 5.1 GB needed | 7.1 GB |
| OLMo 2 1B / 7B | 7B | 5.1 GB needed | 7.1 GB |
| Falcon 3 1B / 3B / 7B | 7B | 5.1 GB needed | 7.1 GB |
| Command R7B | 7B | 5.1 GB needed | 7.1 GB |
| OpenHermes 2.5 | 7B | 5.1 GB needed | 7.1 GB |
How to read this
The NVIDIA Quadro K4100M is a mobile workstation graphics card equipped with 4 GB of GDDR5 memory. This dedicated video memory determines the maximum size of the artificial intelligence models you can run entirely on the hardware. To run a model smoothly without system slowdowns, the model files and the active working memory must fit within this 4 GB physical limit.
The quant column indicates the quantization level used to compress the model weights. Quantization reduces the precision of the numerical values to save space. For example, a Q6_K quant represents a high quality compression that fits a 4B model like Qwen3 4B or Gemma 3 4B into 3.9 GB of video memory. Lower quants like Q4_K_M compress files further to let larger 5B models like Lumina-Next or CogVideoX 2B run within 3.7 GB of memory.
When a model exceeds the 4 GB video memory limit, you must use CPU offload. This technique splits the model layers between your graphics card and your system RAM. We assume your system has 32 GB of system RAM for these calculations. For instance, running Mistral 7B requires 5.7 GB of memory at Q4_K_M, which uses your video memory and 7.7 GB of system RAM. Offloading lets you run larger models like Falcon 3 7B or Command R7B, but it reduces processing speed.
You can run several specialized models locally on this hardware. Image generation models like SDXL Turbo and SDXL Lightning fit into 3.4 GB of video memory using Q6_K quants. Audio models like Fish Speech 1.5 and Orpheus TTS also run within the hardware limits. For vision tasks, Phi-3.5-vision fits into 3.6 GB of video memory using a Q5_K_M quant.
Keep in mind the 4k context caveat when running these local models. The memory figures listed are calculated for a standard context window. If you increase the context length to process longer documents or extended conversations, the memory usage will grow. This extra demand can exceed your 4 GB limit and force the system to slow down or offload data to your system RAM.